Product Search Results

  • Dr. Amy Myers Candida Panel

    This test includes a Candida Albicans antibody profile, CBC with diff and IgA, IgE, IgM (Total Immunoglobulins).

    Test Description:
    There are 3 antibodies that are important to look for when your are measuring your immune system’s response to Candida – IgG, IgA, IgM (Total Immunoglobulins). A CBC offers clues as to how the body’s immune system is functioning and measuring immunoglobulins may also offer clues as to where the immune system is being impacted by Candida.

    Detailed Information:
    Candida normally occurs in the mouth, vagina, or gastrointestinal tract. Candida can become quite problematic if there is an overgrowth of yeast in comparison to healthy gut flora. Antibiotics promote the growth of yeast by destroying both good and bad bacteria in the gastrointestinal tract without deterring the growth of Candida albicans. Without balanced numbers of friendly bacteria such as Lactobacillus acidophilus and Bifidobacteria in the gastrointestinal tract, an environment exists that Candida albicans will thrive in. When this occurs, the body's immune system becomes overwhelmed, not only by the overwhelming presence of Candida, but also by the toxic by-products that Candida produces.

    Candida has the ability to suppress the immune system so it is important to test your total IgG,  IgA, IgM (Immunoglobulins) levels along with the Candida antibodies. Low levels of total IgG, IgA, IgM antibodies  could cause a false negative response to the Candida antibodies, meaning you have Candida but since your immune system is lowered, you are unable to produce a response and your blood test comes back negative. Conversely, high levels of these antibodies indicate that an overgrowth of Candida is present somewhere in the body and that your immune system is reacting to it. A CBC may offer that let may indicate if yeast is present. A low white blood cell count (WBC) has been associated with yeast overgrowth as well as a pattern of high neutrophil and low lymphocyte count.

    Test Preparation for Optimal Results:

    1. No fasting is required but please go in well hydrated for your lab draw.  
    2. Your test results should be finished processing in 7-14 business days.
    3. When your results have finished processing, a copy will be sent directly to you.

    Disclaimer:
    Your health care provider should evaluate a deviation from normal ranges.

    Test code: 
    Dr. Amy Myers Candida Panel
    Cost: 
    $299.00
  • Dr. Amy Myers Thyroid Panel Plus

    Dr. Amy’s Thyroid Plus Panel includes these tests: TSH Free T4, Free T3, Reverse T3, Thyroid Peroxidase Antibodies, Thyroglobulin Antibodies, Ferritin, Vitamin D3 (OH), Selenium – RBC, Zinc – RBC, Magnesium – RBC and a Vitamin A.

    Test Description:
    Dr. Amy strategically constructed this panel in order to review a broader perspective of thyroid function. Thyroid hormone production is not only dependant on a complicated hormone synthesis process, optimal thyroid function is also dependant on a multitude of cofactors, many of those cofactors are evaluated in this panel in concert with specific thyroid function tests.

    Detailed Information:
    Thyroid hormone production is regulated by a feedback loop between the hypothalamus, pituitary gland, and the thyroid gland. Hypothalamic thyrotropin-releasing hormone (TRH) stimulates pituitary thyrotropin (TSH) synthesis and secretion. In turn, TSH stimulates production and release of T4 and T3 from the thyroid gland. When enough T4 is produced, it signals to TRH and TSH that there is enough thyroid hormone in circulation and not to produce more. About 85% of the hormone produced by our thyroid gland is T4, which is an inactive form of the hormone. After T4 is made, a small amount of it is converted into T3, which is the active form of thyroid hormone. To complicate matters, T3 also gets converted into either Free T3 (FT3) or Reverse T3 (RT3). It is the Free T3 that really matters in all of this, since it’s the only hormone that can attach to a receptor and cause your metabolism to rise, keep you warm, keep your bowels moving, mind working, and other hormones in check. The role of Reverse T3 is not well known, however, Dr. Amy has seem it elevated in persons under extreme stress and those who have mercury toxicity.

    And finally, Hashimoto’s thyroiditis, an autoimmune disease, is the most common form of hypothyroidism and its numbers are rising annually. Hashimoto’s thyroiditis is an autoimmune disease is one in which your body turns on itself and begins to attack a certain organ or tissue believing its foreign. Dr. Amy routinely screens all of her patients for autoimmune thyroid disease by ordering Thyroid Peroxidase Antibodies (TPOAb) and Thyroglobulin Antibodies (TgAb).

    Test Preparation for Optimal Results: 
    1. If possible, have the lab collected early in the morning or shortly after waking. For comparison purposes, have subsequent labs collected close to the same time.
    2. To optimize your test results, it is recommended that you fast for 10 -12 hours (water only).  
    3. Refrain from taking supplements (especially those that contain Vitamin A) for at least 72 hours before a Selenium and Vitamin A test.
    4. Your test results should be finished processing in 10 -14 business days.
    5. When your results have finished processing, a copy will be sent directly to you.

    Disclaimer:
    Your health care provider should evaluate a deviation from normal ranges.

    Test code: 
    Dr. Amy Myers Thyroid Panel Plus
    Cost: 
    $499.00
  • Dr. Amy Myers Repeat Thyroid Panel

    Dr. Amy’s repeat thyroid panel includes these tests: TSH, Free T4 and a Free T3

    Test Description:
    This panel was built specifically as a follow up panel to Dr. Amy’s Basic and or Thyroid plus panel. This panel offers is an excellent thyroid screening panel because it includes a TSH, Free T4 and Free T3 hormones.

    Detailed Information:
    After Dr. Amy has evaluated thyroid function with her basic panel or her plus panel, Dr. Amy recommends these tests for follow up testing. It is important to understand how important optimal thyroid function is for every cell and body system we have. Thyroid hormone production is regulated by a feedback loop between the hypothalamus, pituitary gland, and the thyroid gland. Hypothalamic thyrotropin-releasing hormone (TRH) stimulates pituitary thyrotropin (TSH) synthesis and secretion. In turn, TSH stimulates production and release of T4 and T3 from the thyroid gland. When enough T4 is produced, it signals to TRH and TSH that there is enough thyroid hormone in circulation and not to produce more. About 85% of the hormone produced by our thyroid gland is T4, which is an inactive form of the hormone. After T4 is made, a small amount of it is converted into T3, which is the active form of thyroid hormone. From years of clinical practice, Dr. Amy understands just how important each biochemical step of thyroid function and how best to evaluate it in order to help improve the health and well being of those she serves.

    Test Preparation For Optimal Results:
    1. If possible, have the lab collected early in the morning or shortly after waking. For comparison purposes, have subsequent labs collected close to the same time.
    2. For optimal results, please fast for 10-12 hours prior to testing. Please be well hydrated, water only. 
    3. Your test results should be finished processing in 7-14 business days. 
    4. When your results have finished processing, a copy will be sent directly to you.

    Disclaimer:
    Your health care provider should evaluate a deviation from normal ranges.

     

    Test code: 
    Dr. Amy Myers Repeat Thyroid Panel
    Cost: 
    $125.00
  • Glyphosate

    Glyphosate General:
    Glyphosate is the world’s most widely produced herbicide and is the primary toxic chemical in Roundup™, as well as in many other herbicides. In addition, it is a broad-spectrum herbicide that is used in more than 700 different products from agriculture and forestry to home use. Glyphosate was introduced in the 1970s to kill weeds by targeting the enzymes that produce the amino acids tyrosine, tryptophan, and phenylalanine. The enzymes of many bacteria are also susceptible to inhibition by this chemical, thus altering the flora of many animals. Usage of glyphosate has since amplified, after the introduction of genetically modified (GMO) glyphosate-resistant crops that can grow well in the presence of this chemical in soil. In addition, toxicity of the surfactant commonly mixed with glyphosate, polyoxyethyleneamine (POEA), is greater than the toxicity of glyphosate alone (1). In addition, in 2014 Enlist Duo™, a herbicide product which contains a 2,4-dichlorophenoxyacetic acid (2,4-D) salt and glyphosate, was approved for use in Canada and the U.S. for use on genetically modified soybeans and genetically modified maize, both of which were modified to be resistant to both 2,4-D and glyphosate. 2,4-D has many toxic effects of its own and can be measured in the GPL-TOX test.

    Glyphosate and Autism:
    Recent studies have discovered glyphosate exposure to be a cause of many chronic health problems. It can enter the body by direct absorption through the skin, by eating foods treated with glyphosate, or by drinking water contaminated with glyphosate. A recent study (2) stated that a coherent body of evidence indicates that glyphosate could be toxic below the regulatory lowest observed adverse effect level for chronic toxic effects, and that it has teratogenic, tumorigenic and hepatorenal effects that can be explained by endocrine disruption and oxidative stress, causing metabolic alterations, depending on dose and exposure time. The World Health Organization International Agency for Research on Cancer published a summary in March 2015 that classified glyphosate as a probable carcinogen in humans (3). Possible cancers linked to glyphosate exposure include non-Hodgkin lymphoma, renal tubule carcinoma, pancreatic islet-cell adenoma, and skin tumors. Studies have also indicated that glyphosate disrupts the microbiome in the intestine, causing a decrease in the ratio of beneficial to harmful bacteria (4). Thus, highly pathogenic bacteria such as Salmonella entritidis, Salmonellagallinarum, Salmonella typhimurium, Clostridium perfringens, and Clostridium botulinum are highly resistant to glyphosate but most beneficial bacteria such as Enterococcus faecalis, Enterococcus faecium, Bacillus badius, Bifidobacterium adolescentis, and Lactobacillus spp. were found to be moderately to highly susceptible. The relationship between the microbiome of the intestine and overall human health is still unclear, but current research indicates that disruption of the microbiome could cause diseases such as metabolic disorder, diabetes, depression, autism, cardiovascular disease, and autoimmune disease.

    Treatment of glyphosate toxicity should be centered on determining the route of introduction and avoiding future exposure. Eating non-GMO (genetically modified organism) foods and drinking reverse osmosis water are two of the best ways to avoid glyphosate. A recent study showed that people eating organic food had considerably lower concentrations of glyphosate in the urine (2). Drinking extra water may also be beneficial since glyphosate is water soluble. More than 90% of corn and soy used are now of the GMO type. In addition, non-GMO wheat is commonly treated with glyphosate as a drying procedure. Glyphosate is somewhat volatile and a high percentage of rain samples contained glyphosate (2).

    Another study found that glyphosate accumulated in bones. Considering the strong chelating ability of glyphosate for calcium, accumulation in bones is not surprising. Other results showed that glyphosate is detectable in intestine, liver, muscle, spleen and kidney tissue (5). A 54-year-old man who accidentally sprayed himself with glyphosate developed disseminated skin lesions six hours after the accident (6). One month later, he developed a symmetrical parkinsonian syndrome.

    The chelating ability of glyphosate also extends to toxic metals (7). The high incidence of kidney disease of unknown etiology (renal tubular nephropathy) has reached epidemic proportions among young male farm workers in sub-regions of the Pacific coasts of the Central American countries of El Salvador, Nicaragua, Costa Rica, India, and Sri Lanka (8). The researchers propose that glyphosate forms stable chelates with a variety of toxic metals that are then ingested in the food and water or in the case of rice paddy workers, may be absorbed through the skin. These glyphosate-heavy metal chelates reach the kidney where the toxic metals damage the kidney. These authors propose that these chelates accumulate in hard water and clay soils and persist for years, compared to much shorter periods of persistence for non-chelated glyphosate. Furthermore, these chelates may not be detected by common analytical chemistry methods which can only detect free glyphosate, thus dramatically reducing estimates of glyphosate persistence in the environment when metals are high (for example, in clay soil or hard water).

    High correlations exist between glyphosate usage and numerous chronic illnesses, including autism, which is shown in the figure on the first page (9). Other disease incidences with high correlations include hypertension, stroke, diabetes , obesity, lipoprotein metabolism disorder , Alzheimer’s, senile dementia, Parkinson’s, multiple sclerosis, inflammatory bowel disease, intestinal infections, end stage renal disease, acute kidney failure, cancers of the thyroid, liver, bladder, pancreas, kidney, and myeloid leukemia (9). Correlations are not causations, yet they raise concern over the use of a chemical to which all life on earth appears to be exposed.

    Specimen Requirements:
    Urine: 10 mL of first morning urine before food and drink is preferred. The patient must discontinue soy proteins one week prior to collection of specimen (soy bean oil and soy lecithin are considered acceptable).

    Test code: 
    Glyphosate
    Cost: 
    $99.00
  • GPL-TOX: Toxic Non-Metal Chemical Profile General

    Every day, we are exposed to hundreds of toxic chemicals through products like pharmaceuticals, pesticides, packaged foods, household products, and environmental pollution. As we have become more exposed to chemical-laden products and to toxic chemicals in food, air, and water, we have been confronted with an accelerating rate of chronic illnesses like cancer, heart disease, chronic fatigue syndrome, chemical sensitivity, autism spectrum disorders, ADD/AD(H)D, autoimmune disorders, Parkinson’s disease, and Alzheimer’s disease.

    Because exposure to environmental pollutants has been linked to many chronic diseases, The Great Plains Laboratory has created GPL-TOX, a toxic non-metal chemical profile that screens for the presence of 172 different toxic chemicals including organophosphate pesticides, phthalates, benzene, xylene, vinyl chloride, pyrethroid insecticides, acrylamide, perchlorate, diphenyl phosphate, ethylene oxide, acrylonitrile, and more. This profile also includes Tiglyglycine (TG), a marker for mitochondrial disorders resulting from mutations of mitochondrial DNA. These mutations can be caused by exposure to toxic chemicals, infections, inflammation, and nutritional deficiencies.

    Advantages of the GPL-TOX Profile:

    • GPL-TOX screens for 172 different environmental pollutants using 18 different metabolites, all from a single urine sample.
    • GPL-TOX uses the power of advanced mass spectrometry (MS/MS), which is necessary to detect lower levels of certain genetic, mitochondrial, and toxic chemical markers that conventional mass spectrometry often misses.
    • GPL-TOX also includes Tiglylglycine, a marker for mitochondrial damage, which is often seen in chronic toxic chemical exposure.
    • GPL-TOX pairs perfectly with our Organic Acids Test (OAT) and our Glyphosate Test in the Enviro-TOX Panel. This panel offers you comprehensive testing to assess exposure to common environmental toxins and the damage that can be caused by this exposure, all at a great value, and all from one urine sample.

    William Shaw, Ph.D., Director of The Great Plains Laboratory is board-certified in both clinical chemistry and toxicology by the American Board of Clinical Chemistry.

    Envioronmental Pollutants Tested by GPL-TOX:
    Phthalates
    Perhaps the most widespread group of toxic chemicals found in our environment. Phthalates are commonly found in after shave lotions, aspirin, cosmetics, detergents, foods microwaved with plastic covers, oral pharmaceutical drugs, intravenous products prepared in plastic bags, hair sprays, insecticides, insect repellents, nail polish, nail polish remover, skin care products, adhesives, explosives, lacquer, janitorial products, perfumes, paper coatings, printing inks, safety glass, and varnishes. Phthalates have been implicated in reproductive damage, depressed leukocyte function, and cancer. Phthalates have also been found to impede blood coagulation, lower testosterone, and alter sexual development in children. Low levels of phthalates can feminize the male brain of the fetus, while high levels can hyper-masculinize the developing male brain.

    Vinyl Chloride
    Vinyl chloride is an intermediate in the synthesis of several commercial chemicals, including polyvinyl chloride (PVC). Exposure to vinyl chloride may cause central nervous system depression, nausea, headache, dizziness, liver damage, degenerative bone changes, thrombocytopenia, enlargement of the spleen, and death.

    Benzene
    Benzene is an organic solvent that is widespread in the environment. Benzene is a by-product of all sources of combustion, including cigarette smoke, and is released by outgassing from synthetic materials, and is a pollutant released by numerous industrial processes. Benzene is an extremely toxic chemical that is mutagenic and carcinogenic. High exposures to benzene cause symptoms of nausea, vomiting, dizziness, lack of coordination, central nervous system depression, and death. It can also cause hematological abnormalities.

    Pyrethrins
    Pyrethrins are widely used as insecticides. Exposure during pregnancy doubles the likelihood of autism. Pyrethrins may affect neurological development, disrupt hormones, induce cancer, and suppress the immune system.

    Xylenes
    Xylenes (dimethylbenzenes) are solvents found not only in common products such as paints, lacquers, pesticides, cleaning fluids, fuel and exhaust fumes, but also in perfumes and insect repellents. Xylenes are oxidized in the liver and bound to glycine before eliminated in urine. High xylene levels may be due to the use of certain perfumes and insect repellents. High exposures to xylene create an increase in oxidative stress, causing symptoms such as nausea, vomiting, dizziness, central nervous system depression, and death. Occupational exposure is often found in pathology laboratories where xylene is used for tissue processing.

    Styrene
    Styrene is used in the manufacturing of plastics, in building materials, and is found in car exhaust fumes. Polystyrene and its copolymers are widely used as food-packaging materials. The ability of styrene monomer to leach from polystyrene packaging to food has been reported. Occupational exposure due to inhalation of large amounts of styrene adversely impacts the central nervous system, causes concentration problems, muscle weakness, tiredness and nausea, and irritates the mucous membranes of the eyes, nose, and throat.

    Organophosphates
    Organophosphates are one of the most toxic groups of substances used throughout the world. They are often used as biochemical weapons and terrorist agents, but are most commonly used in pesticide formulations. Organophospates are inhibitors of cholinesterase enzymes, leading to overstimulation of nerve cells, causing sweating, salivation, diarrhea, abnormal behavior, including aggression and depression. Children exposed to organophosphates have more than twice the risk of developing pervasive developmental disorder (PDD), an autism spectrum disorder. A study done in the San Francisco Bay area found that in California agricultural areas, children born to mothers living within 500 meters of fields where organochlorine pesticides were used were more than 6 times more likely to develop autism than children whose mothers did not live near such fields. ASD risk increased with the poundage of organochlorines applied and decreased with distance from field sites. Maternal organophosphate exposure has been associated with various adverse outcomes including having shorter pregnancies and children with impaired reflexes.

    MTBE and ETBE
    MTBE and ETBE are gasoline additives used to improve octane ratings. Exposure to these compounds is most likely due to groundwater contamination, and inhalation or skin exposure to gasoline or its vapors and exhaust fumes. MTBE has been demonstrated to cause hepatic, kidney, and central nervous system toxicity, peripheral neurotoxicity, and cancer in animals. Since the metabolites of these compounds are the same, ETBE may be similarly toxic.

    2, 4-Dicholorophenoxyacetic (2,4-D)
    A very common herbicide that was a part of Agent Orange, used by the United States during the Vietnam War to increase visibility for war planes, by destroying plant undergrowth and crops. It is most commonly used in agriculture on genetically modified foods, and as a weed killer for lawns. Exposure to 2, 4-D via skin or oral ingestion is associated with neuritis, weakness, nausea, abdominal pain, headache, dizziness, peripheral neuropathy, stupor, seizures, brain damage, and impaired reflexes. 2, 4-D is a known endocrine disruptor, and can block hormone distribution and cause glandular breakdown.

    Diphenyl Phosphate
    This is a metabolite of the organophosphate flame retardant triphenyl phosphate (TPHP), which is used in plastics, electronic equipment, nail polish, and resins. TPHP can cause endocrine disruption. Studies have also linked TPHP to reproductive and developmental problems.

    Acrylamide
    Acrylamide can polymerize to form polyacrylamide. Polyacrylamide is used in many industrial processes such as plastics, food packaging, cosmetics, nail polish, dyes, and treatment of drinking water. Food and cigarette smoke are also two major sources of exposure. Acrylamide has been found in foods like potato chips, French fries, and many others such as asparagus, potatoes, legumes, nuts, seeds, beef, eggs, and fish. Asparagine, which is found in these foods can produce acrylamide when cooked at high temperature in the presence of sugars. High levels of acrylamide can elevate a patient’s risk of cancer. In addition, acrylamide is known to cause neurological damage.

    Perchlorate
    This chemical is used in the production of rocket fuel, missiles, fireworks, flares, explosives, fertilizers, and bleach. Studies show that perchlorate is often found in water supplies. Many food sources are also contaminated with perchlorate. Perchlorate can disrupt the thyroid’s ability to produce hormones. The EPA has also labeled perchlorate a likely human carcinogen. Patients that are high in perchlorate can use a reverse osmosis water treatment system to remove the chemical from their water supply.

    1,3 Butadiene
    This is a chemical made from the processing of petroleum. It is often a colorless gas with a mild gasoline-like odor. Most of this chemical is used in the production of synthetic rubber. 1,3 Butadiene is a known carcinogen and has been linked to increased risk of cardiovascular disease. Individuals that come into contact with rubber, such as car tires, could absorb 1,3 Butadiene through the skin. The increased use of old tires in the production of crumb rubber playgrounds and athletic fields is quite troubling because children and athletes may be exposed to toxic chemicals this way.

    Propylene Oxide
    This chemical is used in the production of plastics and is used as a fumigant. Propylene oxide is used to make polyester resins for textile and construction industries. It is also used in the preparation of lubricants, surfactants, and oil demulsifiers. It has also been used as a food additive, an herbicide, a microbicide, an insecticide, a fungicide, and a miticide. Propylene oxide is a probable human carcinogen.

    1-Bromopropane (1-BP)
    1-Bromopropane is an organic solvent used for metal cleaning, foam gluing, and dry cleaning. Studies have shown that 1-BP is a neurotoxin as well as a reproductive toxin. Research indicates that exposure to 1-BP can cause sensory and motor deficits. Chronic exposure can lead to decreased cognitive function and impairment of the central nervous system. Acute exposure can lead to headaches.

    Ethylene Oxide
    Ethylene oxide is used in many different industries including agrochemicals detergents, pharmaceuticals, and personal care products. Ethylene oxide is also used as a sterilizing agent on rubber, plastics, and electronics. Chronic exposure to ethylene oxide has been determined to be mutagenic to humans. Multiple agencies have reported it as a carcinogen. Studies of people exposed to ethylene oxide show an increased incidence of breast cancer and leukemia. Caution is needed with ethylene oxide because it is odorless at toxic levels.

    Acrylonitrile
    Acrylonitrile is a colorless liquid with a pungent odor. It is used in the production of acrylic fibers, resins, and rubber. Use of any of these products could lead to exposure to acrylonitrile. Smoking tobacco and cigarettes is another potential exposure. Exposure to acrylonitrile can lead to headaches, nausea, dizziness, fatigue, and chest pains. The European Union has classified acrylonitrile as a carcinogen.

    GPL-TOX is Recommended for The Following Disorders:

    • Alzheimer's Disease
    • Amyotrophic Lacteroclerosis (ALS)
    • Anorexia Nervosa
    • Anxiety Disorder
    • Apraxia
    • Arthritis
    • Asthma
    • Attention deficit (ADD)
    • Attention deficit with hyperactivity (ADHD)
    • Autism
    • Autoimmune disorders
    • Bipolar disorder
    • Cancer
    • Cerebral palsy
    • Chronic fatigue syndrome
    • Crohn's disease
    • Depression
    • Developmental disorder
    • Down Syndrome
    • Epilepsy
    • Failure to thrive
    • Fibromyalgia
    • Genetic diseases
    • Irritable bowel syndrome
    • Learning disability
    • Mitochondria disorder
    • Multiple sclerosis
    • Obsessive compulsive disorder (OCD)
    • Occupational exposures
    • Parkinson's disease
    • Peripheral neuropathy
    • Schizophrenia
    • Seizure disorders
    • Systemic lupus erythematosus
    • Tic disorders
    • Tourette syndrome
    • Ulcerative colitis

    Mitochondrial Disorders:
    The GPL-TOX profile tests for Tiglyglycine (TG), one of the most specific markers for mitochondrial disorders resulting from mutations of mitochondrial DNA. These mutations can result from exposure to toxic chemicals, infections, inflammation, and nutritional deficiencies. Mitochondria are important in all cells in the body, but are especially important to organs that utilize large amounts of energy, such as the muscles, heart, and brain. The mitochondria also have several other important functions in the cell, including steroid synthesis, calcium regulation, free radical production, and the induction of apoptosis or programmed cell death, all of which are involved in the pathogenesis of numerous disorders. The marker used in the GPL-TOX profile indicates mitochondrial dysfunction by monitoring a metabolite that is elevated in mitochondrial deficiency of cofactors such as NAD+, flavin-containing coenzymes, and Coenzyme Q10. Disorders associated with mitochondrial dysfunction include autism, Parkinson's disease, and cancer.

    Metabolites of Pollutants Tested by GPL-TOX:
    2-Methylhippuric Acid (2MHA), 3-Methylhippuric Acid (3MHA), 4-Methylhippuric Acid (4MHA)
    These are metabolites of xylenes, solvents found in paints, lacquers, cleaning agents, pesticides, and gasoline. Exposure to xylenes generates methylhippuric acid isomers. Avoid/reduce exposure to these substances.

    N-acetyl phenyl cysteine (NAP)
    NAP is a metabolite of benzene. Benzene is a solvent that is widespread in the environment. It is found in cigarette smoke and gasoline, and is a byproduct of all types of combustion, including motor vehicle exhaust. Treatment consists of removing sources of exposure.

    Phenylglyoxylic Acid (PGO)
    Exposure to environmental styrene may slightly increase phenylglyoxylic and mandelic acid. Reduce exposure by eliminating the use of plastic and styrofoam containers for cooking, reheating, eating or drinking. Elimination of styrene can be accelerated by supplementing with glutathione and N-acetyl cysteine (NAC).

    2-Hydroxyisobutyric Acid (2HIB)
    2-Hydroxyisobutyric acid is formed endogenously as a product of branched-chain amino acid degradation and ketogenesis. This compound is also the major metabolite of gasoline octane enhancers such as MTBE and ETBE. Elevated levels indicate environmental exposure and very high values have been reported in genetic disorders.

    Monoethyl Phthalate (MEP)
    MEP from diethyl phthalate is the most abundant phthalate metabolite found in urine. Diethyl phthalate is used in plastic products. Elevated values indicate exposure from various possible sources. Elimination of phthalates may be accelerated by sauna treatment.

    Dimethylphosphate (DMP) & Diethylphosphate (DEP)
    DMP and DEP are major metabolites of many organophosphate pesticides. Reduce exposure by eating organic foods and avoiding use of pesticides in your home or garden. Living near agricultural areas or golf courses and areas regularly sprayed with pesticides will increase exposure. Elimination of organophosphates can be accelerated by sauna treatment.

    3-Phenoxybenzoic Acid (3PBA)
    3-Phenoxybenzoic acid is a metabolite of pyrethroid insecticides. Elimination can be accelerated by sauna treatment.

    2,4-Dichlorophenoxyacetic Acid (2,4-D)
    2,4-D was an ingredient in Agent Orange, and is most commonly used in agriculture of genetically modified foods, and as a weed killer for lawns. Reduce exposure by eating organic foods and avoiding use of pesticides in your home or garden.

    Tiglylglycine (TG)
    TG is a marker for mitochondrial dysfunction. Mutations of mitochondria DNA may result from exposure to toxic chemicals, infections, inflammation, and nutritional deficiencies.

    N-acetyl-S-(2-carbamoylethyl)-cysteine
    NAE is a metabolite of acrylamide, which is detoxified through a two-step process. First acrylamide is metabolized by the cytochrome P450s. Second it is conjugated to glutathione in order to make it more water soluble. Acrylamide is used in many industrial processes such as plastics, food packaging, cosmetics, nail polish, dyes, and treatment of drinking water. High levels of acrylamide can elevate a patient’s risk of cancer and cause neurological damage. Supplementation with glutathione can assist in the elimination of this compound.

    Diphenyl Phosphate
    This is a metabolite of the organophosphate flame retardant triphenyl phosphate (TPHP), which is used in plastics, electronic equipment, nail polish, and resins. TPHP can cause endocrine disruption. Studies have also linked TPHP to reproductive and developmental problems.

    Perchlorate
    Perchlorate is used in the production of rocket fuel, missiles, fireworks, flares, explosives, fertilizers, and bleach. Studies show that perchlorate is often found to contaminate water supplies and food sources. It can disrupt the thyroid’s ability to produce hormones. The EPA has also labeled perchlorate a likely human carcinogen. Patients that are high in perchlorate can use a reverse osmosis water treatment system to remove perchlorate.

    N-Acetyl (3,4-Dihydroxybutyl) Cysteine (NABD)
    NADB is a metabolite of 1,3 butadiene, which is evident of exposure to synthetic rubber such as tires. 1,3 butadiene is a known carcinogen and has been linked to increased risk of cardiovascular disease. Individuals that come into contact with rubber, such as car tires, could absorb 1,3 butadiene through the skin.

    N-Acetyl (2,Hydroxypropl) Cysteine (NAHP)
    NAHP is a metabolite of propylene oxide which is used in the production of plastics and as a fumigant. It is also used in the preparation of lubricants, surfactants, and oil demulsifiers and as a food additive, an herbicide, a microbicide, an insecticide, a fungicide, and a miticide. Propylene oxide is a probable human carcinogen.

    N-Acetyl (Propyl) Cysteine (NAPR)
    NAPR is a metabolite of 1-bromopropane. Chronic exposure can lead to decreased cognitive function and impairment of the central nervous system. Acute exposure can lead to headaches.

    2-Hydroxyethyl Mercapturic Acid (HEMA)
    HEMA is a metabolite of ethylene oxide, which is used in the production of agrochemicals, detergents, pharmaceuticals, and personal care products. Chronic exposure to ethylene oxide has been determined to be mutagenic to humans. HEMA is also a metabolite of vinyl chloride and halopropane, which are used in many commercial chemical processes such as foam glueing, dry cleaning, and in the production of solvents. Supplementation with glutathione should assist in the detoxification process of these chemicals.

    N-Acetyl (2-Cyanoethyl) Cysteine (NACE)
    NACE is a metabolite of acrylonitrile, which is used in the production of acrylic fibers, resins, and rubber. Acrylonitrile is metabolized by the cytochrome P450s and then conjugated to glutathione. Supplementation with glutathione should assist in the detoxification of acrylonitrile.

    Recommendations for Detoxification of Chemicals:
    If you or a patient has had a GPL-TOX profile and/or a Glyphosate test run and found moderate-high levels of any compounds, there are things you can do to help your body eliminate the toxins and to prevent future exposures. The first steps to reducing the amount of toxins presently in the body are to switch to eating only organic food and drinking water that has common toxins, including pesticides filtered out. Most conventional food crops are exposed to larger and larger doses of pesticides and herbicides, and by switching to organic you will prevent exposure to hundreds of these toxicants. Many of these chemicals have also contaminated our water supplies. Installing a high-quality water filtration system in the home that eliminates them is important to do and there are several options available.

    The next step to avoiding future exposures is to change the products you use on a daily basis – from food and beverage containers to beauty and cleaning products. Instead of using plastic water bottles and food containers, switch to glass or metal. Never microwave food in plastic or styrofoam containers and do not drink hot beverages from plastic or styrofoam cups. Make sure your shampoo, soaps, lotions, and other beauty products are free of phthalates. Use cleaning products made from natural ingredients or make your own at home.

    To eliminate toxins from the body, we highly recommend exercise and the use of saunas, especially infrared sauna therapy to rid many chemicals through sweat. Infrared sauna is superior to conventional sauna because it reaches deeper into the body, increasing the circulation in the blood vessels, and causing the body to start to releasing many of the chemicals stored in body fat.

    There are two supplements that are particularly useful in helping the body detoxify. The first is glutathione, or its precursor N-acetyl cysteine. Glutathione is one of the most common molecules used by the body to eliminate toxic chemicals. If you are constantly exposed to toxicants your stores of glutathione could be depleted. The second supplement is vitamin B3 (niacin). Some may not enjoy the flushing that can happen when taking niacin, however, this flushing is from the blood vessels dilating, which is useful in the detoxification process. If sensitive to the flushing, start with the lowest recommended dose and work up from there.

    Test code: 
    GPL-TOX: Toxic Non-Metal Chemical Profile General
    Cost: 
    $250.00
  • Adrenal Stress Profile (4X cortisol and DHEA) BioHealth BH #201

    This profile is used to evaluate the adrenal glands and hormone balance (Not available in NY, MA, PA, RI & NJ).

    Test Description:
    In the event of adrenal exhaustion, underlying causes must be determined through additional lab testing and investigation into environmental and lifestyle factors; while also supporting the adrenals with nutritional protocols and lifestyle modifications.

    This profile is used to evaluate the adrenal glands and hormone balance. In the event of adrenal exhaustion, underlying causes must be determined through additional lab testing and investigation into environmental and lifestyle factors; while also supporting the adrenals with nutritional protocols and lifestyle modifications.

    When the body is under chronic stress, pregnenolone, the precursor to all other steroidal hormones, is diverted to produce cortisol (known as pregnenolone steal or cortisol escape). This is to the detriment of all other steroidal hormones (such as DHEA and its metabolites, including progesterone, testosterone, and the estrogens). As pregnenolone is diverted to cortisol, DHEA depletion begins. The result is an elevated cortisol to DHEA ratio. A normal ratio is approximately 5:1 to 6:1.

    Test Results:

    1. Your test results should be finished processing in approximately 10 -14 business days one the lab has received the test kit.
    2. When your results have finished processing, a copy will be sent directly to you.
    Disclaimer:
    Your health care provider should evaluate a deviation from normal ranges.

    Test code: 
    Adrenal Stress Profile (4X cortisol and DHEA) BioH
    Cost: 
    $329.00
  • Vitamin D, 1,25-Dihydroxy

    Vitamin D, 1,25-Dihydroxy Vitamin D. Also known as: 1,25-Dihydroxycholecalciferol, Vitamin D, 1,25-Dihydroxy. This test is frequently used to measure Vitamin D levels in the blood.

    Test Description:
    This test may be used when evaluating a Vitamin D deficiency or to evaluate parathyroid function or bone metabolism.

    Detailed Information:
    Vitamin D is certainly an important topic and news about Vitamin D can be found all over social media, health journals and commercials. The only way to know your vitamin D status is to test for it. There are two major metabolites of vitamin D: Vitamin D 25 OH and Vitamin 1, 25 - Dihydroxy. Vitamin D 1,25-Dihydroxy is the most potent of the various vitamin D metabolites. Its action stimulates calcium absorption in the intestine and its production is tightly regulated through concentrations of serum calcium, phosphorus, and parathyroid hormone.

    Vitamin D is rapidly metabolized in the liver to form 25-hydroxy (OH) vitamin D. Additional hydroxylation of 25-OH vitamin D takes place in the kidney by 1-alpha hydroxylase, under the control of parathyroid hormone, to yield 1,25-dihydroxy vitamin D. Vitamin D 1,25-Dihydroxy levels are frequently decreased in hypoparathyroidism and in chronic renal failure.

    Test Preparation for Optimal Results:
    No fasting required.

    Disclaimer:
    Your health care provider should evaluate a deviation from normal ranges.

    Test code: 
    Vitamin D, 1,25-Dihydroxy
    Cost: 
    $89.00
  • Dr. Amy Myers Thyroid Panel

    Dr. Amy recommends these test be checked for a thyroid function evaluation.

    Test Description:
    This panel includes a TSH Free T4, Free T3, Reverse T3, Thyroid Peroxidase Antibodies and Thyroglobulin Antibodies.

    Detailed Information:
    It has been estimated that between 3 and 10 million people actually suffer from an overactive thyroid, or hyperthyroidism. Dr. Amy is well aware that many of these imbalances are associated with internal as well as external factors to include infectious disease and ever increasing toxins found in our environment. Thyroid hormone is required by every cell on our bodies which means thyroid function directly impacts gastrointestinal function, liver detoxification, our adrenal hormones, brain function and bone health to name a few. Based on years of clinical experience, up to date research and hands on patient care, Dr. Amy has strategically built thyroid panels to help identify the root cause of thyroid imbalances.

    Test Preparation For Optimal Results:

    1. If possible, have the lab collected early in the morning or shortly after waking. For comparison purposes, have subsequent labs collected close to the same time.
    2. For optimal results, please fast for 10-12 hours prior to testing. Please be well hydrated, water only. 
    3. Your test results should be finished processing in 7-14 business days. 
    4. When your results have finished processing, a copy will be sent directly to you.

    Disclaimer:
    Your health care provider should evaluate a deviation from normal range.

    Test code: 
    Dr. Amy Myers Thyroid Panel
    Cost: 
    $254.00
  • Comprehensive Stool Analysis with Parasitology x3 (Doctor’s Data)

    The Comprehensive Stool Analysis with Parasitology x 3 is used to objectively evaluate the status of beneficial and imbalanced commensal bacteria, pathogenic bacteria, yeast/fungus and parasites.

    Test Description:
    Gastrointestinal complaints are among the most common in medical care. This comprehensive profile helps pinpoint the causes of gastrointestinal symptoms and chronic systemic conditions, and measures key markers of digestion, absorption and inflammation. Using growth-based culture, the standard of practice in clinical microbiology, as well as sensitive biochemical assays and microscopy, this thorough profile evaluates the status of beneficial and pathogenic microorganisms including aerobic and anaerobic bacteria, yeast and parasites. Antimicrobial susceptibility testing to prescriptive and natural agents is also performed for appropriate bacterial and fungal species at no additional charge. Parasitology testing can include one-, two- or three-day collection, based on practitioner preference.

    Detailed Information:
    The Comprehensive Stool Analysis with Parasitology x 3 is an invaluable non-invasive diagnostic assessment that permits practitioners to objectively evaluate the status of beneficial and imbalanced commensal bacteria, pathogenic bacteria, yeast/fungus and parasites. Precise identification of pathogenic species and susceptibility testing greatly facilitates selection of the most appropriate pharmaceutical or natural treatment agents.

    Important information regarding the efficiency of digestion and absorption can be gleaned from the measurement of the fecal levels of elastase (pancreatic exocrine sufficiency), fat, muscle and vegetable fibers, and carbohydrates. Inflammation can significantly increase intestinal permeability and compromise assimilation of nutrients. The extent of inflammation, whether caused by pathogens or inflammatory bowel disease (IBD), can be assessed and monitored by examination of the levels of biomarkers such as lysozyme, lactoferrin, white blood cells and mucus. These markers can be used to differentiate between inflammation associated with potentially life-threatening inflammatory bowel disease (IBD), which requires lifelong treatment, and less severe inflammation that can be associated with irritable bowel syndrome (IBS) which is frequently due to the presence of enteroinvasive pathogens. Lactoferrin is only markedly elevated prior to and during the active phases of IBD, but not with IBS. Monitoring fecal lactoferrin levels in patients with IBD can therefore facilitate timely treatment of IBD, and the test can be ordered separately. Since the vast majority of secretory IgA (sIgA) is normally present in the GI tract, where it prevents binding of pathogens and antigens to the mucosal membrane, it is essential to know the status of sIgA in the gut. sIgA is the only bona fide marker of humoral immune status in the GI tract.

    Cornerstones of good health include proper digestion of food, assimilation of nutrients, exclusion of pathogens and timely elimination of waste. To obtain benefits from food that is consumed, nutrients must be appropriately digested and then efficiently absorbed into portal circulation. Microbes, larger-sized particles of fiber, and undigested foodstuffs should remain within the intestinal lumen. Poor digestion and malabsorption of vital nutrients can contribute to degenerative diseases, compromised immune status and nutritional deficiencies. Impairment of the highly specific nutrient uptake processes, or compromised GI barrier function, as in "leaky gut syndrome," can result from a number of causes including:

    • Low gastric acid production
    • Chronic maldigestion
    • Food allergen impact on bowel absorptive surfaces
    • Bacterial overgrowth or imbalances (dysbiosis)
    • Pathogenic bacteria, yeast or parasites and related toxic irritants
    • The use of NSAIDs and antibiotics

    Impairment of intestinal functions can contribute to the development of food allergies, systemic illnesses, autoimmune disease, and toxic overload from substances that are usually kept in the confines of the bowel for elimination. Efficient remediation of GI dysfunctions incorporates a comprehensive guided approach that should include consideration of elimination of pathogens and exposure to irritants, supplementation of hydrochloric acid, pancreatic enzymes and pre- and probiotics, and repair of the mucosal barrier.

    Sample Result.

    Test Preparation for Optimal Results:
    See Collection Information

    Test Results:
    8-14 business days one the lab has received the test kit.

    Disclaimer:
    Your health care provider should evaluate a deviation from normal ranges.

    Test code: 
    Comprehensive Stool Analysis with Parasitology x3
    Cost: 
    $385.00
  • Zinc - RBC

    This blood test measures Zinc levels in the red blood cells.

    Test Description:
    This blood test measures Zinc levels in the erythrocytes. This test may be more useful due to its high concentrations of zinc enzymes such as anhydrase.

    Detailed Information:
    Zinc affects multiple aspects of the immune system, from the skin barrier to gene regulation within lymphocytes (a type of white blood cell). In fact, zinc is essential for the production of white blood cells and studies show that people with zinc deficiency are more susceptible to pathogens. Zinc is a crucial trace element required for the growth and healthy development of all living organisms. Zinc deficiency can lead to immune system dysfunction and impairments in growth, cognitive dysfunction, poor carbohydrate metabolism and hormonal function. Low dietary zinc is associated with hypogonadism, low Insulin Growth Factor-1, low testosterone and low levels of the thyroid hormone Free T4. It is estimated that nutritional zinc deficiency affects over 2 billion people worldwide, especially those in developing countries.

    The USDA's 1996 Continuing Survey of Food Intake has documented that over 70% of Americans do not consume the recommended daily allowance for zinc. Zinc is second to iron in body content and is found largely in the intracellular components of tissues in the liver, pancreas, kidney, bone, muscles, eyes, prostate, fingernails and skin. It is a cofactor for more than 300 known enzymes and plays a crucial role in maintaining the healthy function of DNA, RNA and transcription factors. Zinc is necessary to maintain normal serum testosterone. Inadequate zinc levels prevent the pituitary gland from releasing luteinizing and follicle stimulating hormones, which stimulate testosterone production. Zinc deficiency may have an impact on the male prostate gland. Research is ongoing to assess a possible correlation between zinc levels and prostate health. Zinc competes with copper and may contribute to a copper imbalance.

    Test Preparation for Optimal Results:
    No fasting required.

    Disclaimer:
    Your health care provider should evaluate a deviation from normal ranges.

    Test code: 
    Zinc - RBC
    Cost: 
    $99.00
  • Selenium - RBC

    This blood test measures selenium levels within the red blood cells.

    Test Description:
    This blood test measures selenium levels within the red blood cells and selenium is present in high concentrations in erythrocyte glutathione peroxidase. Selenium is an essential trace element. It is widely recognized as a key nutrient in cancer prevention and is a crucial cofactor for the conversion of T4 to T3 in healthy thyroid function.

    Detailed Information:
    Selenium may be a little-known mineral, but studies show that it is essential for regulating excessive immune responses and chronic inflammation in autoimmune diseases. It is also a vital nutrient for proper thyroid function, and studies show that increasing selenium in autoimmune thyroid patients decreases their thyroid antibodies. The enzyme that converts T4 (the inactive form of thyroid hormone) to T3 (the active form), is a selenium-dependent enzyme, so without enough selenium your thyroid hormones are stuck in their inactive state, causing hypothyroidism symptoms. Sufficient levels of selenium also help prevent and reverse autoimmune thyroid. When your body converts iodide (the form iodine that you ingest, such as table salt, which is sodium iodide) into iodine, the process produces hydrogen peroxide. Hydrogen peroxide is an oxidant and damages thyroid cells, which can trigger an autoimmune response. Selenium acts to neutralize the hydrogen peroxide, and research has shown that increasing selenium levels in patients with autoimmune thyroid disease reduces their level of thyroid peroxidase antibodies (TPOAb).

    Selenium protects genes from inflammatory disease processes such as dementia, stroke, heart disease, diabetes and asthma. Selenium plays a crucial role by helping the body detoxify naturally from heavy metals such as cadmium. Cigarettes are a significant source of cadmium exposure worldwide. Cadmium has been found in toxic levels in fertilizers, pesticides and PVC plastics. Cadmium toxicity affects the lungs, brain, kidneys and bones and may lead to problems such as fatigue, confusion, depression and cardiac arrhythmias.

    Test Preparation for Optimal Results:
    No fasting required.

    Disclaimer:
    Your health care provider should evaluate a deviation from normal ranges.

    Test code: 
    Selenium - RBC
    Cost: 
    $99.00
  • Vitamin A

    This test is used to evaluate the amount of Vitamin A in the blood.

    Test Description:
    We have twice as many Vitamin A receptors than Vitamin D receptors. Vitamin A is needed for growth and for strong teeth and bones, as well as for healthy skin and for eye health. Sources of Vitamin A are liver, dairy products, fish liver oils, dark green and yellow-orange vegetables and in some fruits.

    Detailed Information:
    Vitamin A is an oil- soluble vitamin also known as retinol. Beta Carotene is not actually a vitamin. It is a precursor of Vitamin A. Vitamin A has specific maintenance roles in our body and carotenoids such as beta carotene are stored in reserves and are easily converted into Vitamin A. Research shows that beta carotenes also act as antioxidants. Vitamin A supports vision, skin growth and repair, bone growth as well as protection from diseases such as cancer, macular degeneration, atherosclerosis and Alzheimer’s Disease. Deficiencies can be caused by lack of Vitamin A in the diet, malabsorption problems such as diarrhea or fat malabsorption & problems with recurrent infections. Insufficient levels of vitamin A are a major nutritional problem throughout the world to include the United States. Vitamin A is present in liver, fish liver oils, dairy products, dark green and yellow-orange vegetables, and in fruits. Beta-carotenes are antioxidants that protect cells against oxidative damage that predisposes cellular balances that may lead to inflammatory processes such as caner. Carotenoids, including beta-carotene are very low in people with Alzheimer’s disease. Carotenoids are found in dark colored fruits and vegetables.

    Test Preparation for Optimal Results:
    For optimal results, please fast a minimum of eight hours. No foods containing vitamin A should be eaten 48 hours prior to the lab test.

    Disclaimer:
    Your health care provider should evaluate a deviation from normal ranges.

    Test code: 
    Vitamin A
    Cost: 
    $42.00
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